Danielius Serapinas Abstract Alpha-1 antitrypsin (AAT) is the main circulating serine proteinase inhibitor. A number of studies suggest that AAT can also exhibit biological activity independent of inhibition of serine proteases. The aim of the study was to make experimental investigation of AAT influence on monocytes stimulated by bacterial endotoxyn . AAT affects monocyte responses…
Danielius Serapinas, Mantas Sauspreskis, Justinas Žiūraitis, Diana Barkauskienė, Marius Žemaitis, Raimundas Sakalauskas Abstract It is essential to confirm or exclude the diagnosis of cystic fibrosis in time and with accuracy in order to avoid inappropriate testing. The aims of this study was to determine features of Cl ions concentration in patients sweat test that were…
Juozas Kapturauskas, Edmundas Širvinskas Abstract Increasing numbers of patients with diabetes mellitus are referred to cardiac surgery. Biguanides are still first-line treatment for type 2 diabetes in all over the world. According preoperative guidelines, oral diabetes medications should be held on the day of surgery because of increased risk of lactic acidosis, induced by Metformin…
Andrius Macas, Limas Kupčinskas, Giedrius Barauskas, Darius Trepenaitis, Juozas Kupčinskas, Aurelija Petkevičiūtė, Asta Mačiulienė Abstract Portopulmonary hypertension is one of the complications for people with end stage chronic liver disease. This condition occurs to 5-8% of people, who need liver transplantation, and it causes a higher risk of perioperative complications or these patients are even…
Aurelija Maziukienė, Aldona Jakštaitė, Giedrė Šilkūnienė, Kristina Kmieliūtė, Antanas Gulbinas, Žilvinas Dambrauskas Abstract Pancreatic adenocarcinoma is one of the most aggressive human malignancies with high mortality rates. Low survival rates are due to late diagnosis at advanced stages of the disease. High invasiveness and chemoresistance of pancreatic adenocarcinoma at least partially could be related to…
Albertas Daukša, Aldona Jakštaitė, Augustina Gasianec, Žilvinas Dambrauskas Abstract Pancreatic cancer has one of the worst prognoses of allgastrointestinal malignancies. One of the key proteins in themechanism of apoptosis is apoptosis protease-activating factorAPAF-1. The aim of this study was to determine expression ofAPAF-1 mRNA in pancreatic cancer. Real time PCR for APAF-1 mRNA was performed…
Danielius Serapinas Abstract Miscarriage and induced abortion are life events thatcan potentially cause mental distress. The objective of this study was literature review and to performcase study to determine whether there are any differencesin the patterns of psychological symptomsafter these two events and to point the importance of informed consent. In our study 20 women…
