THE EFFECT OF ASCORBIC ACID ON ENDOTHELIAL GLYCOCALYX ALTERATIONS DURING CARDIAC SURGERY

Volume 35, Number 7 (2025)

Urtė Valūnaitė, Eva Nausevič, Judita Andrėjaitienė Abstract Cardiac surgery is associated with oxidative stress and systemic inflammation, which both contribute to postope­rative organ dysfunction. Vitamin C is a pleiotropic, an­tioxidant, and potentially organ–protective micronutrient. It also influences coagulation and inflammation, and its application might prevent organ damage. Complications after heart surgery have received considerable attention…

NAFLD PATHOGENESIS AND CLINICAL ASSOCIATIONS WITH CARDIOVASCULAR DISEASES

Volume 34, Number 3 (2024)

Julija Valaitienė Abstract Non-alcoholic fatty liver disease (NAFLD) is an expan­ding issue in prevention and treatment. The central patho­logical processes of NAFLD comprise pathological lipid accumulation resulting in insulin resistance, oxidative stress, mitochondrial dysfunction, inflammation, and endoplasmic reticulum stress. NAFLD is firmly associ­ated with a raised risk of major cardiovascular events. This literature review seeks…

ANTIOXIDANT COMPLEMENTS AND SUPPLEMENTS POTENTIAL USE IN ONCOLOGY

Volume 21, Number 7(79) (2011)

Saulė Uleckienė Abstract free radicals, antioxidants, oxidative stress. Free radicals are products of normal metabolism. Endogenous antioxidative system neutralise the extensive quantities of free radicals. The pathological processes as inflammation or cancer result in augmenting the formation of free radicals and oxidative stress occurs. For neutralisation of oxidative stress the antioxidants are used. Much remains unknown concerning the mode of action…