OFF-LABEL TREATMENT IN PEDIATRICS – ASSOCIATIONS, LATEST RECOMMENDATIONS
Urtė Oniūnaitė, Lina Jankauskaitė Abstract Off-label treatment is often seen in pediatrics, especially in pediatric intensive care and neonatal departments. It is linked to a broad range of factors, including restriction of pharmacological studies for ethical reasons, different pharmacokinetic and pharmacodynamic properties of medicines due to age and physiological differences in children, and the difficulty…