MUTATIONS OF LEBER’S HEREDITARY OPTIC NEUROPATHY AND THEIR ASSOCIATION WITH CLINICAL MANIFESTATION

Paulina Steniulytė, Simona Vaitkutė, Rasa Liutkevičienė Abstract Leber‘s hereditary optic neuropathy (LHON) is a rare disorder that mainly presents in males in their young age. The majority of cases are caused by three primary maternally inherited mtDNA point mutations (m.3460G > A, m.11778G > A, and m.14484T > C) that affect su­bunits 4, 6, and…

INTERVENTIONS PRIOR AND DURING THE ORTHODONTIC TREATMENT FOR ORTHODONTICALLY INDUCED WHITE SPOT LESIONS

Nerija Spaičytė, Ieva Gudelevičiūtė, Indrė Migonienė, Arūnas Vasiliauskas Abstract Objective. To evaluate the efficiency of various interven­tions performed before and during orthodontic treatment which aim to reduce the incidence of WSL. Materials and methods. Using PRISMA guidelines in search of clinical trials published between 2017 and 2022, a literature analysis was performed. This search was…

Risk Factors For Violent Behaviour Among Forensic Psychiatric Patients

Aldona Šileikaitė, Ilona Čėsnienė, Arūnas Germanavičius Abstract Forensic psychiatry is specific area where legal, clinical and social aspects are involved. Moreover it is important to evaluate and protect both sides the public and persons who are not guilty by reason of insanity. The most prevalent mental disorders among forensic psychiatry patients are psychotic disorders (especially…

Occipital Condyle Fracture: Analysis of a Case Report and Literature Review

Vytautas Ragaišis, Evaldas Keleras Abstract Occipital condylar fractures caused by high-energy blunttrauma to the craniocervical junction are very rare. It may lead toan incomplete understanding of the entity of this pathology andcan be underdiagnosed becouse this condition likely occurs withgreater frequency. The clinical presentation is highly variable:severe neck pain, caudal cranial nerve (IX-XII) palsy Collet-Sicardsyndrome,…

Neurosarcoidosis Complicated with Hydrocephalus

Antanas Romas Gvazdaitis, Kęstutis Jacikevičius, Loreta Radvinskienė, Saulius Taroza Abstract Neurosarcoidosis is rare appearance of sarcoidosis with involvement of neural tissue. Neurosarcoidosis may damage any neural tissue, but the most often involved places are cerebral nerves, meninges and hypothalamus. Hydrecephalus is very rare manifestation of neurosarcoidosis. There is presented the young man case with intense…

Principles of neuropathic pain treatment

Vytautas Kasiulevičius Abstract Summary Neuropathic pain results from damage to or dysfunction of the peripheral or central nervous system, rather than stimulation of pain receptors. Diagnosis is suggested by pain out of proportion to tissue injury, dysesthesia (eg, burning, tingling), and signs of nerve injury detected during neurologic examination. Although neuropathic pain responds to opioids,…