Changes Of Brain Injury Markes (S100B AND NSE) In Newborns And Infants Perioperative Period

Ilona Razlevičė, Danguolė Rugytė, Andrius Macas Abstract The aim of our study was to evaluate the influence of perioperative period (first 24 hours) on brain specific proteins S100B and NSE concentration in plasma and to correlate it with intraoperative cerebral oxygen saturation (rSO2c) in neonates and infants, Methods: The prospective observational clinical study included 46…

Neuronal Apoptosis in Neonates and Infants and Perioperative Period: is There a Relationship?

Ilona Šuškevičienė, Milda Nekrašienė, Danguolė Česlava Rugytė, Alina Vilkė, Tomas Bukauskas, Diana Bilskienė, Andrius Macas Abstract In these latter decades neurotoxicity of general anesthetics has been demonstrated in neonatal animal models. These data raised a concern about the safety of neonatal and pediatric anesthesia. However, prospective epidemiological studies in humans are still ongoing. Biological markers,…

Antibiotic Prescribing for Children and Neonates Hospitalized in Children’s Hospital, Affiliate of Vilnius University Hospital Santariskiu Clinics

Vytautas Usonis, Vilija Gurkšnienė Abstract The irrational prescribing and usage of antimicrobial agents increase antimicrobial resistance and reduces the effectiveness of the treatment of some infections. Both in Lithuania and Europe standardized and comparable data on pediatric and neonatal antibiotic prescribing is lacking. The aim of this study was to determine antibiotic prescribing prevalence for…