Loss of Proapoptotic Gene Apaf-1 Expression in Pancreatic Cancer
Albertas Daukša, Aldona Jakštaitė, Augustina Gasianec, Žilvinas Dambrauskas Abstract Pancreatic cancer has one of the worst prognoses of allgastrointestinal malignancies. One of the key proteins in themechanism of apoptosis is apoptosis protease-activating factorAPAF-1. The aim of this study was to determine expression ofAPAF-1 mRNA in pancreatic cancer. Real time PCR for APAF-1 mRNA was performed…