Genes Important in the Pathogenesis of Colorectal Cancer
Danguolė Raulinaitytė, Rasa Ugenskienė, Rasa Jančiauskienė, Elona Juozaitytė, Laura Kairevičė Kairevičė Abstract Colorectal cancer results from the intracellular accumulation of both genetic and epigenetic changes that transform normal glandular epithelium into invasive adenocarcinoma. Each stage of colorectal tumor formation involves different genes. It is believed that changes of MMR and APC genes are important for…