Neuronal Apoptosis in Neonates and Infants and Perioperative Period: is There a Relationship?

Volume 23, Number 1(86) (2013)

Ilona Šuškevičienė, Milda Nekrašienė, Danguolė Česlava Rugytė, Alina Vilkė, Tomas Bukauskas, Diana Bilskienė, Andrius Macas Abstract In these latter decades neurotoxicity of general anesthetics has been demonstrated in neonatal animal models. These data raised a concern about the safety of neonatal and pediatric anesthesia. However, prospective epidemiological studies in humans are still ongoing. Biological markers,…

Near-infrared spectroscopy as an index of brain and tissue oxygenation

Volume 21, Number 5(77) (2011)

Alina Vilkė Abstract Summary Cerebral hypoxia is a major contributor to poor neurologic outcome in a variety of clinical cases but its detection remains problematic. Measurement of cerebral oxygenation is widely used to assess the balance between cerebral metabolic supply and demand although standard bedside methods of measuring cerebral oxygenation have significant limitations. Near-infrared spectroscopy…