Millions of women use the hormonal contraceptive worldwide, however hormonal contraceptive use is actual and controversal problem, because it is certainly associated non only with protection against pregnancy, but also with pulmonary thromboembolism, stroke, cervical cancer. New evidence is now emerging that taking the oral contraceptive pill might significantly alter both female and male mate choice by removing the mid-cycle change in preferences. Here, we review support for such conclusions and speculate on the consequences of pillinduced choice of otherwise less-preferred partners for relationship satisfaction, durability and, ultimately, reproductive outcomes. The article analyses the pathophysiological mechanisms of hormonal contraceptives, their influence to fertilization, procreation, mutagenic mechanisms and clinical case about 43 years patient with pulmonary throboembolism, which determinative factor was use of hormonal contrareptives.
Keyword(s): Hormonal contraceptives, procreation, pulmonary thromboembolism, risk factors.
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