Radiosensitivity Of Chondrosarcomas: A Case Of Spinal Chondrosarcoma

Aista Plieskienė Abstract Chondrosarcomas are slow-growing, malignant mesenchymal tumours characterized by the formation of cartilage by the tumour cells, high-grade malignant lesions with aggressive local behavior and metastatic potential. As chondrosarcomas grow slowly, with a relatively low fraction of dividing cells, and radiotherapy acts at dividing cells, chondrogenic tumors are considered relatively radiotherapy resistant. Radiotherapy…

A New Approach In The Study Of Individual Radiosensitivity In Cancer Patients

Aista Plieskienė, Rima Ladygienė, Žygimantas Vaisiūnas, Kamilė Guogytė, Vinsas Janušonis, Julius Žiliukas Abstract Radiotherapy is used with curative intention in most cancer patients. Individual radiosensitivity has a crucial impact on radiotherapy related side effects. Analysis of cytogenetic damage in peripheral blood lymphocytes induced by ionizing radiation is commonly used for biodosimetry. The applicability of the…