PHYSICAL EXERCISE, BDNF, AND COGNITIVE AGING: MECHANISMS, EVIDENCE, AND CLINICAL IMPLICATIONS

Kimberley Mvetimbo Tambo, Vaiva Hendrixson Abstract Aim: To review the biological mechanisms, clinical evi­dence, and translational implications of exercise-induced BDNF modulation in the context of cognitive aging, and to examine the role of physical activity as a modifiable lifestyle factor supporting brain health. Methods: A narrative review of current scientific litera­ture was conducted, including experimental…