Fabry Nefropathy
Marius Miglinas, Pranas Šerpytis, Urtė Gargalskaitė, Justė Danieliūtė, Algirdas Utkus Abstract Anderson-Fabry disease (AFD) is a X-linked lysosomal storage disorder caused by mutations of the GLA gene that encodes α-galactosidase A, what causes intracellular accumulation of globotriaosylceramide. The main manifestations of AFD are pain attacks, acroparasthesias, cutaneous angiokeratomas, hypohydrosis, kidney, heart and cerebrovascular disorders. Late…