Impaired Neurogenesis Following Treatment for CNS Malignancies

Aista Plieskienė, Tomas Daukšas Abstract Radiation therapy is common standard treatment method for treatment of central nervous system (CNS) malignancies. The risk associated with this therapeutic modality is neurotoxicity. The literature reviews the mechanisms of radiation induced failure of neurogenesis. Cranial radiation therapy is associated with a progressive decline in cognitive function, prominently memory, specifically…