PHYSICAL EXERCISE, BDNF, AND COGNITIVE AGING: MECHANISMS, EVIDENCE, AND CLINICAL IMPLICATIONS

Volume 36, Number 4 (2026)

Kimberley Mvetimbo Tambo, Vaiva Hendrixson Abstract Aim: To review the biological mechanisms, clinical evi­dence, and translational implications of exercise-induced BDNF modulation in the context of cognitive aging, and to examine the role of physical activity as a modifiable lifestyle factor supporting brain health. Methods: A narrative review of current scientific litera­ture was conducted, including experimental…

EXPLORING THE LINK BETWEEN MYOKINE CONCENTRATION AND EXERCISE INTENSITY IN YOUNG INDIVIDUALS

Volume 35, Number 1 (2025)

Julija E. Köhnke, Damian L. Mialkowskyj, Vaiva Hendrixson Abstract Physical activity offers numerous health benefits, inclu­ding improved brain function, weight management, dise­ase prevention, and enhanced muscle and bone strength. This study aimed to explore the link between exercise intensity and myokine concentrations, specifically Brain- Derived Neurotrophic Factor (BDNF) and Irisin, in young individuals. Fifteen participants…