Ingrida Marija Pacauskienė, Eglė Stasiukonė, Benita Vaišvilaitė
This review evaluates the possible relationship between periodontal disease and adverse pregnancy outcomes, especially pre-eclampsia, a major pregnancy complication.A literature search of electronic databases PubMed (www.ncbi.nlm.nih.gov/ pubmed), „Journal of Periodontology“ (www.joponline.org) was performed for articles published 2002 to 2014. 22 studies analizing relationship between periodontitis and pre – eclampsia were included, including 19 case – control studies and 3 systematic reviews. 5 studies (case – controls) analizing relationship between periodontitis and pregnant women with pre-eclampsia included. 10 studies (case – controls) analizing relationshiop between periodontitis and adverse pregnancy outcomes included. 17 sudies reported positive association between periodontitis and preeclampsia, while 5 studies showed no significant association. 5 studies found positive association between periodontitis and pregnant women with pre – eclampsia. 6 studies reported possitive association between periodontitis and adverse pregnancy outcomes, 4 studies showed no significant association. It appeared difficult to compare these studies, due to variations in definitions of periodontal disease and pre-eclampsia, differences of methodology and different characteristics of studied groups. Further studies for stronger evidence are required.
Keyword(s): periodontitis; preeclampsia; preterm birth; low birth weight
Full Text: PDF