Henrikas Kazlauskas, Elena Bovina, Geriuldas Žiliukas
Hemorrhagic transformation (HT) is a common complication ofacute ischemic stroke; its influence on the results of the treatmenthas however not been fully established. The aim of the study wasto evaluate the relationship between hemorrhagic transformationand clinical characteristics in patients with acute ischemic stroke.Retrograde analysis of data from medical records of 28 patients(including 13 patients with stroke after intravenous thrombolysis),treated in the stroke unit of the Klaipeda university hospital in theperiod of 2009-2013, was applied. The control group consistedof 15 randomly selected patients, treated within the same timeperiod in the stroke unit, who have not been diagnosed with HT.SPSS 17.0 software package was used for statistical analysis.Following preliminary calculations, binomial logistic regression(Enter method) was applied in order to asses possible factors ondisease course. All tests were statistically significant at p<0.05.The study concluded that hemorrhagic transformation in patientswith acute ischemic stroke is significantly associated with chronicatrial fibrillation, and that antithrombotic treatment initiated duringthe first days after acute ischemic stroke does not influence theoccurrence of HT.
Keyword(s): acute ischemic stroke, hemorrhagic transformation
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