Edita Kizevičienė, Laimutė Jonaitienė, Jurgita Daukšienė, Eglė Dieninytė, Rimantas Pečiūra


A large part of medications produced in the pharmacy consist of semi-solid formulations. Semi-solid formulation of medications is quickly produced, easily applied, and is able to deliver a wide range of pharmaceutical molecules locally. The authors of this paper have conducted the research with the aim to identify the range of vegetable oils, used in the production of semi-solid pharmaceutical formulations, in Lithuanian pharmacies. The following methods were used to perfrom the investigation: analysis of scientific sources and professional literature, telephone survey, presenting respondents a previously developed questionnaire survey containing closed type questions. The principle of a snowball was selected. The following scientific references and professional literature were analyzed ̶ reference books containing information about 346 medicines on doctor‘s prescription produced in the pharmacies in Lithuania. The research revealed that by the year 2014 in accordance with the doctor‘s prescription pharmacies could produce extemporaneous medicines of seventy-one title (21% of all the presented in manuals) for various health disorders, containing lipophilic substances: vegetable, mineral oils, animal fats. Some formulations contain several lipophilic substances. The following semi-solid pharmaceutical formulations are produced in Lithuanian pharmacies – ointments, liniments, creams and gels, for the production of which olive, sunflower, castor and almond oils are used. For the production of semi-solid pharmaceutical formulations 88,6%, of surveyed pharmacies use olive oil, 80,0% of pharmacies use sunflower oil, 65,7% -castor oil and 22,9% of pharmacies use almond oil.

Keyword(s): vegetable oils; semi-solid pharmaceutical formulations; extemporaneus drugs.
DOI: 10.5200/sm-hs.2016.089
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