Rūta Kinderytė, Martynas Špečkauskas
Proliferative vitreoretinopathy (PVR) is defined as retinal pigment epithelium proliferation associated growth and contraction of avascular fibrous – cellular membranes within the vitreous body. It develops after rhegmatogenous retinal detachment, when liberated cells of retinal pigment epithelium gain access through retinal tear to vitreous body, or after serious retinal surgery, in which extensive retinopexy by lasering or cryotherapy is performed, or in cases of serious penetrating eye injuries. While retinal surgery is improving PVR gains more importance. Despite effective initial treatment pathological membranes progress on surface of the retina, that causes its traction and deterioration of visual functions. This paper reviews data from latest publications about PVR pathogenic mechanisms, risk factors, treatment and its complications, as well as prevention.
Keyword(s): proliferative vitreoretinopathy; rhegmatogenous retinal detachment; pathogenesis; pars plana vitrectomy; scleral buckling; treatment strategy
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