Arvydas Valavičius, Lina Penkauskaitė, Julius Ališauskas, Algimantas Šimkaitis, Loreta Radvinskienė


The article provides an overview of treated patients with suspected lung cancer who overcome CT guided transthoracic core needle biopsy of peripheral lung nodule in order to specify diagnosis. Study was performed at Klaipėda University hospital in the year 2014. Review consists of etiology, epidemiology, histology, clinical outcomes and treatment management of peripheral lung nodule. The results were compared to findings in the literature. Conclusions. CT guided transthoracic core needle biopsy is a safe and effective diagnostic method based on the data collected in Klaipėda University hospital in 2014. Transthoracic CT guided core needle biopsy is diagnostically accurate procedure with a successful histological specimen acquirement rate 90,82 percent of cases. There were no major complications occurred after this procedure. It can be said that CT guided transthoracic core needle biopsy is diagnostically sensitive procedure. Based on the study, as much as 19,04 percent of patients with peripheral small cell lung cancer are recommended chemotherapy or radiotherapy instead of surgical treatment. Findings of this study recommend performing transthoracic CT guided core needle biopsy on all peripheral lung nodules due to their high malignancy rate. In reference to our data 84 (77 percent) of peripheral lung nodules were malignant. Lung nodule`s histology allows to predict it`s progression and clinical outcomes and gives opportunity for individualised provides options in the treatment of disease.

Keyword(s): peripheral lung nodule; transthoracic core needle lung biopsy; histology; peripheral lung cancer treatment.
DOI: 10.5200/sm-hs.2015.069
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