EFFECT OF VITAMIN D ON OSSEOINTEGRATION OF DENTAL IMPLANTS

Purpose. The aim of this study was to review the current literature to evaluate the effects of vitamin D on osseoin­tegration of dental implants in humans.

Material and methods. The PRISMA Statement’s metho­dological guidelines were followed in the systematic re­view of the scientific literature. The Elsevier and PubMed databases were searched from October 2012 to October 2022 using different combinations of the following terms: dental implant, bone implant contact, vitamin D and os­seointegration. The current systematic review format was modified to primarily summarize the relevant data.

Results. 3 prospective clinical studies with humans as subjects met the inclusion criteria. The amount of inser­ted titanium implants ranged between 32 to 122. It was shown that changes in the vitamin D concentration were positively linked with bone loss/growth at the implant site. Patients who took vitamin D supplements and had low vitamin D levels after the implant loading had a positive impact on bone level changes in the process of osseointegration.

Conclusion. There is some evidence to support the con­cept that serum vitamin D levels may play a significant role in osseointegration, marginal bone loss, and success of dental implants. Further investigation is required to maintain these assumptions.