Izabelė Lanauskaitė
Abstract
Mitral valve prolapse (MVP) is a common pathology with a population prevalence of 2–3 % (1). This disorder generally has a good prognosis (2), despite the fact that recent observations suggest that sudden cardiac death from ventricular arrhythmias associated with MVP can occur more often, with an estimated annual risk ranging from 0,2 % to 1,9 % (3, 4). Arrhythmic mitral valve prolapse is defined as mitral valve prolapse that is associated with complex ventricular arrhythmias (3). Imaging studies of the heart assist in looking for markers that help select patients with a higher risk of fatal arrhythmic events (5). Between 33% and 78% of the patients with malignant ventricular arrhythmias at risk of sudden cardiac death have been found to have an inverted and biphasic T-wave in the inferior and lateral leads. Signs of left ventricular transmural replacement fibrosis in papillary muscles 88% or inferolateral left ventricular basal wall 93% (6) and mitral annular disjunction were also found (7).
Surgical repair theoretically relieves stretch on the papillary muscles and facilitates ventricular remodelling, leading to a reduction in ventricular arrhythmias (8). Catheter ablation using invasive electroanatomic mapping is a promising treatment option for patients with arrhythmic mitral valve prolapse, but the positive effects on patient survival have not yet been well documented (9). The aim of the study is to review the available literature on the diagnosis and treatment methods of arrhythmic mitral valve prolapse.
Keyword(s): arrhythmic mitral valve prolapse; cardiac death; mitral annular disjunction; myocardial fibrosis.
DOI: 10.35988/sm-hs.2025.159
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