Brigita Vaidachovičiūtė, Lukas Šemeklis, Sandra Rimšelytė
Abstract
Percutaneous liver biopsy is an important diagnostic tool applied for the evaluation and management of liver diseases. Currently liver biopsy has three major roles: for diagnosis of liver diseases, for assessment of prognosis (disease staging) and/or the evaluation of therapeutic management efficacy. Due to increasing number of performed liver biopsies on the daily basis it is of great importance to assess the reasonability of indications and the rate of diagnosis confirmed. The aim of the study. To evaluate indications and histological findings of percutaneous liver biopsies performed at the Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Department of Gastroenterology. Methods. We performed a retrospective analysis of 515 patients, who have undergone ultrasound guided percutaneous liver biopsies at the Lithuanian University of Health Science Kaunas Clinics, Department of Gastroenterology. The data of patients age, sex, confirmed diagnosis and histological findings were collected. Results. Histological findings confirmed clinical diagnosis in 67,96% (N=350) of cases, 29,32% (N=151) of clinical diagnosis was not confirmed or denied by histological findings and 2,72% (N=14) of specimens were uninformative, p<0,0001. Histological diagnosis in focal liver diseases group (79,48 proc., N=182) was confirmed more often compared to diffuse liver diseases group (58,87 proc., N=156), p<0,0001. Conclusions. Histological findings confirmed clinical diagnosis in most cases. Clinical diagnosis was confirmed by histological findings more often in focal liver diseases cases than in diffuse liver diseases.
Keyword(s): percutaneous liver biopsy; indications for liver biopsy; liver tumour; hepatitis.
DOI: 10.5200/sm-hs.2017.034
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