Ernesta Pilnikovaitė, Gerda Falkauskaitė, Audra Banišauskaitė, Justina Jurevičiūtė

Abstract

This case report presents a 34-year-old immunocompro­mised male with multiple sclerosis on long-term B-cell depletion therapy, developing severe acute myocarditis (AM) complicated by life-threatening arrhythmias. The initial presentation mimicked acute coronary syndrome (ACS) and pulmonary pathology, delaying diagnosis. Cardiac magnetic resonance imaging (CMR) was cru­cial for confirming diffuse myocardial involvement and guiding management. This case emphasizes the value of early CMR in immunosuppressed patients with atypical presentation, where conventional diagnostic tools may be insufficient.

Keyword(s): acute viral myocarditis, cardiac magnetic resonance, immunodeficiency, ocrelizumab, multiple sclerosis.

DOI: 10.35988/sm-hs.2025.409
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