A REVIEW OF CORTICOSTEROID THERAPY IN SEPTIC SHOCK: CONTROVERSIES AND CONSENSUS

Septic shock, a life-threatening condition, is treated with corticosteroids (CS), but their effectiveness remains de­bated. While some studies show benefits in reducing mortality and vasopressor use time, others find no si­gnificant impact. Corticosteroids can stabilize hemody­namics, especially in patients with adrenal insufficiency or refractory shock, but side effects like hyperglycemia require monitoring. Current guidelines suggest using CS for patients unresponsive to fluid resuscitation and vaso­pressors. However, optimal dosing, timing, and tapering strategies need further research to improve outcomes.