Agnė Talačkaitė, Daumantas Radzevičius, Audrius Ivanauskas

Abstract

Pancreatic neuroendocrine tumors (PNETs) are rare cancers of pancreatic islet cells, comprising 1–2% of pancreatic neoplasms with a rising incidence. Their presentation depends on tumor growthhormone secretion; most are nonfunctioning, while functioning tumors produce hormones such as insulin. Treatment remains challenging and the role of immunotherapy in well-differentiated PNETs is not yet established.

Keyword(s): Pancreatic neuroendocrine tumors, insulinoma.

DOI: 10.35988/sm-hs.2026.230

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