Milda Krivickaitė, Tatjana Orlovskytė, Anželika Chomičienė, Jūratė Grigaitienė, Raimondas Meškauskas, Matilda Bylaitė-Bučinskienė
Abstract
Churg-Strauss syndrome (CSS) is a rare, systemic necrotising small and medium size vessel vasculitis of unknown origin. It was described initially by Churg and Strauss in 1951. It is now classified as an antineutrophil cytoplasmic antibody (ANCA) associated vasculitis. CSS specific signs, which differentiate this syndrome from other small vessel vasculites are late onset asthma, extravascular necrotising granulomas, blood and tissue eosinophilia. According to literature, skin changes are seen in more than half of CSS patients and in some cases are the first signs of the disease. Symptoms of skin or other organ damage and skin biopsy results should alert clinicians about CSS presence and may help to prescribe appropriate etiopathogenetic treatment. This article presents a case report of rare CSS and a literature review.
Article in Lithuanian
Keyword(s): Churg-Strauss syndrome (CSS); vasculitis; eosinophils; ANCA-associated vasculitis; Churg-Strauss granuloma
DOI: 10.5200/sm-hs.2013.120
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